Cisco Webex, Online seminar
(線上演講 Cisco Webex)
Graph-theoretical Stability Analysis, Part 1: The Bridge Between Network Structure and Dynamics
Marc R. Roussel (University of Lethbridge)
Abstract
One of the central problems in biochemical modeling is that of uncertainty: we often don't know the reactions that occur in a cell or tissue very precisely, and even when we do, we hardly ever know all of the parameters. We are nevertheless interested in knowing whether a given model explains observed phenomenology. Traditionally, the connection between model and experiment involved a lot of guesswork, particularly about parameters. In this talk, I will describe a parameter-free method for determining whether a mass-action (bio)chemical model is capable of multistability, oscillations or Turing patterning based on the structure of a graphical representation of its reaction network. The technique will be illustrated with examples, some simple, and one from a larger model for bilateral development.
Meeting number (access code): 2512 395 0639
Meeting password: pZ5Z7mfSm5b
