Cisco Webex, Online seminar
(線上演講 Cisco Webex)
The Role of Detailed Balance in Kinetic Proofreading Models and in Signalling Systems
Eugenia Franco (University of Bonn)
Abstract
The detailed balance is a property of macroscopic systems that are obtained starting from an underlying time-reversible microscopic model. It states that each elementary process (for instance, each chemical reaction) is in equilibrium with its reverse process. Even if, at the microscopic level, we expect chemical reactions to satisfy the so-called detailed balance condition, biochemical systems are often modeled by systems of equations for which detailed balance fails. This can be justified when the system is in contact with "reservoirs" that are out of equilibrium. In this talk I will discuss the relation between the detailed balance property and two important properties of certain chemical systems. The first property that I will discuss is the capability of kinetic proofreading networks to discriminate between different ligands. The second property that I will discuss is the adaptation property (i.e., the fact that some chemical networks respond to gradients instead of absolute values of signals) of signalling systems.
Meeting number (access code): 2510 486 2706
Meeting password: yhCxvddt425
Organizers: Chueh-Hsin Chang (CCU), Jia-Yuan Dai (NTHU), Bo-Chih Huang (CCU), Chih-Chiang Huang (CCU), Chang-Hong Wu (NYCU)
